Our work on 'hidden diversity' in unbinned contigs is now published in @natmicrobiol.nature.com :
www.nature.com/articles/s41...
See the linked threads for more details!
Latest Posts by Phil Hugenholtz
MBE Call for Papers on the Major Transitions of Life
MBE is excited to launch our newest Call for Papers on the Major Transitions of Life, covering all aspects of phylogenomic research.
🔗 academic.oup.com/mbe/pages/call-for-papers-on-the-major-transitions-of-life
Guest Editors:
Davide Pisani
Anja Spang
#evobio #molbio #phylogenetics
Micro-scale spatial metagenomics opens a new era in microbiome ecology
@cp-trendsmicrobiol.bsky.social Opinion from @mizrahilab.bsky.social
www.cell.com/trends/micro...
Metagenomic mining reveals extensive novelty, enhanced biodegradation potential, and untapped biosynthetic capacity in Chinese oilfield microbiomes journals.asm.org/doi/full/10.... #jcampubs
Redox chemistry of early Earth and the origin of life www.nature.com/articles/s42... #jcampubs
Figure 1 shows the conceptual workflow of the algorithm. It first loads the configuration file and the input data of one or multiple binned metagenomes, yet evaluates each bin individually. It then iteratively processes each candidate bin in the input, going through the refinement tasks, potentially multiple times. The refinement either stops when the last step or a preset stop task have been reached or an unrecoverable error has been encountered. The algorithm tasks can be configured individually.
🤯 Manual MAG refinement? Still doing it by hand??
We’ve been there... You could just leave those messy, ill-assigned contigs/scaffolds in your data for NCBI to pick up during your submission…
…OR you could add itBins, our new automated MAG refiner by @jmk-ude.bsky.social, to your pipeline!! 🔥
The SeqCode Committee has opened the call for applications to the SeqCode Prize 2026, sponsored by ISME.
@isme-microbes.bsky.social
Myloasm, our long-read metagenome assembler, is now published! w/ @mgmarin.bsky.social and @lh3lh3.bsky.social
Very rewarding after > a year of development and countless hours thinking about assembly. Thanks to beta testers, Li lab, and reviewers who gave very helpful feedback.
rdcu.be/famFj
How much protein diversity can Life on Earth actually generate?
With DIAMOND DeepClust, we show how billions of proteins across the tree of life can be clustered at low-identity for downstream analytics tasks.
📚Paper: www.nature.com/articles/s41...
💻Code: github.com/bbuchfink/di...
Aerobic sister lineage of breviates has gene-rich mitochondrial genomes
#microbiology #eukaryotes #mitochondria #protists #MicroSky #ProtistsOnSky
@cellpress.bsky.social
www.cell.com/current-biol...
New paper in mSystems! 🧵 - how much of your metagenome is actually bacterial/archaeal DNA? For many samples, nobody knows.
We built SingleM prokaryotic_fraction (SPF) to answer this, then ran it on >100,000 public metagenomes. 🧬🖥️🦠
Here's what we found 👇
doi.org/10.1128/msystems.01062-25
A novel planctomycetotal isolate from subsurface percolates belongs to the novel species Anatilimnocola aquadivae sp. nov. in the family Pirellulaceae
#microbiology #bacteria #NewSpecies #taxonomy #MicroSky
doi.org/10.1038/s415...
Image of the cover of the 1st volume of ISME Host Microbe a new official journal of the International Society for Microbial Ecology. Cover images shows a plant stomata with bacteria around and entering.
Excited to announce our new journal from @isme-microbes.bsky.social ISME Host Microbe is live and now accepting submissions. Look forward to receiving your papers! #Microsky 🧫 🦠
Are you interested in how to predict functions of natural product biosynthetic gene clusters (BGCs) and their products? And/or do you love metallophores and would love to identify their producers in microbiomes? Check out @zachreitz.bsky.social 's new paper!
elifesciences.org/articles/109... 1/n
The recovery of 12,789 genomes revealed the diversity, function, and microbial interactions of the geothermal spring microbiome www.biorxiv.org/content/10.64898/2026.03...
A very good likeness!
Genomic insights into adaptation and microevolution of two novel non-AOA #Nitrososphaeria, Acidarchaeum fankouense and Thermosulfuris yongpingense, in acid mine drainage ecosystems www.sciencedirect.com/science/arti...
Oops, typo in the family name in the abstract
Apolloniradiicaulis salifontis gen. nov., sp. nov., a New Prosthecate Aerobic Anoxygenic Phototroph Isolated from Lake Winnipegosis Region Salt Springs
#microbiology #NewSpecies #taxonomy #MicroSky
doi.org/10.3390/micr...
Thermophilic bacteria employ a contractile injection system in hot spring microbial mats
#microbiology #thermophiles #bacteria #MicroSky
@isme-microbes.bsky.social
doi.org/10.1093/isme...
Phenogenomics reveals the ecology and evolution of Trichoderma fungi for sustainable agriculture
-in @natmicrobiol.nature.com by Andrei Steindorff (@jgi.doe.gov) et al from Irina Druzhinina (at @rbgkew.bsky.social), Feng Cai, Igor Grigoriev, and a large network
www.nature.com/articles/s41...
With Eugene Koonin, we propose a concept of “the selfish ribosome”, under which evolution of life is viewed as a ribosomal takeover, where the ribosome evolved to consume most of the cell’s resources, while other cellular componentry ensures the propagation of the ribosome. arxiv.org/abs/2602.23268
Calibrating for absolute microbiome abundances without spike-ins www.biorxiv.org/content/10.6... #jcampubs
I have the same cat
Huge news 🌍🧬
The Protist 10,000 Genomes Project is joining the Earth BioGenome Project.
Protists may represent the majority of eukaryotic diversity — yet only a tiny fraction have reference genomes.
Time to change that. 🚀✨
Learn more 👉 ngdc.cncb.ac.cn/p10k/
#EBP #Protists #Genomics #TreeOfLife
Metax looks really nice for taxonomic profiling: www.biorxiv.org/content/10.6...
Beyond thrilled to share that our study has been published!
This project encompasses years of work, including my thesis research on Asgard archaea in the @archaeal.bsky.social lab at @utmsi.bsky.social and
@texasscience.bsky.social!!!
#MicroSky #ArchaeaSky 1/12
#NatMicroPicks
Aerobic archaeal-eukaryotic ancestor? 🦠🫁
The ancestor of eukaryotes may have combined hydrogen metabolism with aerobic respiration, shaping early cellular complexity.
#MicroSky
www.nature.com/articles/s41...