🎧 Tune in to our latest episode!
Dr. Amanda Lund at the NYU Grossman School of Medicine joins us to talk about how lymphatic vessels actively regulate #immune responses rather than simply serving as passive conduits.
🔊 Listen now: https://bit.ly/4e1qwWh
Neuron-derived mitochondrial DNA (mtDNA) activates microglia via the Z-DNA binding protein 1 (ZBP1)-mediated pathway in mild traumatic brain injury
www.pnas.org/doi/abs/10.1...
New Journal for ImmunoTherapy of Cancer position article and guidelines: "Spatial and phenotypic plasticity of B cells in remodeling the tumor microenvironment" https://jitc.bmj.com/content/14/3/e014745 #JITC #cancer 🧪
New Journal for ImmunoTherapy of Cancer position article and guidelines: "Spatial and phenotypic plasticity of B cells in remodeling the tumor microenvironment" jitc.bmj.com/content/14/3...
#JITC #cancer 🧪
🎥 This is no April Fool's joke. We're hosting a live show at #AAI2026!
Join the Immunology Podcast on Friday, April 17 at 11:00 AM at IMMUNOLOGY2026 for an in-depth conversation on emerging immunotherapies for solid tumors with Drs. Charles Sentman and Giulia Escobar.
Online now: Distinct tissue niches contribute to prostate tissue-resident memory CD8+ T cell differentiation and heterogeneity
We are just two weeks away from IMMUNOLOGY2026™! 🎉
Will we see you in Boston for AAI's premier all-immunology event? We're looking forward to seeing so many incredible scientists and immunology professionals. What lecture or session are you most looking forward to?
🔗 https://bit.ly/4ovupVf
UPEC subverts neutrophils
Uropathogenic E coli regulatory system DanRI is induced by nucleosomes present in NETs. DanRI regulates broad cellular responses and dampens neutrophil responses by attenuating reactive oxygen species production & NET formation
www.cell.com/cell-host-mi...
📢 New in Science Immunology!
Researchers led by Dr. Shivani Srivastava at @fredhutch.org have demonstrated that CAR T resistance to checkpoint therapy can be overcome by restoring c-Jun alongside PD-L1 blockade.
📜: https://bit.ly/4sGZA2s
🎧: https://bit.ly/4sYIflI
Structure of SARS-CoV-2 spike in complex with its co-receptor the neuronal cell adhesion protein contactin1
www.biorxiv.org/content/10.6...
Check out our new preprint. Cool structure by Sabrina Krepel with Bert Janssen.
Thanks to @danielhurdiss.bsky.social @utrechtvirology.bsky.social #covid #pais
Scientists led by Dr. Rodney King at the University of Alabama at Birmingham have shown that anti-carbohydrate #antibodies develop after birth into a diverse, antigen-shaped B cell repertoire.
👀 Read the study: https://bit.ly/3NQMVLm
🔊 Hear the discussion: https://bit.ly/4sYIflI
Weekend read: Catalog of human oral microbiome
Human reference oral microbiome (HROM) comprises 72,641 genomes from 3,426 species, including 2,019 novel species. HROM reveals disease-assoc. species & ectopic oral species in gut predictive of disease
www.cell.com/cell-host-mi...
In our latest episode, we discuss new work from the lab of Dr. Sing Sing Way at Cincinnati Children’s Hospital.
It shows that newborns with E. coli #sepsis lack protective maternal antibodies, and maternal priming can provide protection.
1️⃣ https://go.nature.com/40rtn2U
2️⃣ https://bit.ly/4sYIflI
For decades, impact in science has been reduced to a number.
But the founder of @altmetric.com, Dr. Euan Adie (@mrstew.bsky.social), explains that impact is far more subjective than we like to admit.
Listen to the latest episode of the Lab Coats & Life™ Podcast, out now! 🎧 #PhDLife
🆕 @utah.edu and @stanfordmedicine.bsky.social researchers, in collaboration with scientists from @columbiauniversity.bsky.social have engineered a class of T cells that are stronger and more precise at killing prostate cancer cells. @science.org
📄: https://bit.ly/40GokvN
🗞️: https://bit.ly/4rPPc7F
Congrats to Dr. Patrick Wilson and his lab on their new @nature.com study! 🎉
They show that early #flu infections imprint the immune system, biasing later responses and reducing effectiveness against new strains.
🗒️: https://go.nature.com/4siqU7a
🎧: https://bit.ly/4sYIflI
Structural and genetic basis of #HIV-1 envelope V2 apex recognition by rhesus broadly neutralizing antibodies. From Roark, Habib, Shaw, Kwong, Shapiro et al.: rupress.org/jem/article/...
📘 Updates on the Immune Responses to #Tuberculosis & #HIV rupress.org/jem/collecti...
#KSTB26 #KSHIVVax26
Thanks for joining the show!
In our latest episode, we chat with Dr. Mansour Haeryfar (@haeryfar.bsky.social at Western University about all things #MAITCells!🎙️
We dive deep into the therapeutic potential of these cells across a range of conditions.
🎧 Listen now: https://bit.ly/4sYIflI
A large number of purple triangles
Researchers from the Hammond and Irvine labs have tackled the challenge of immune monitoring in cancer by developing the first bandage-like microneedle patch that can sample the body’s immune responses painlessly from the skin.
www.eurekalert.org/news-release...
Tissue-restricted secondary TCR engagement drives the transition from stem-like to CD200+ Egr2hi arthritogenic Th17 cells @natimmunol.nature.com
www.nature.com/articles/s41...
📢 AAI has introduced a number of new networking opportunities to increase attendee connection and scientific collaboration at IMMUNOLOGY2026™ in Boston!
📝 Register today to build your immunology community: https://bit.ly/46g64fU
Hitting the hidden: arming the immune system for the next zoonotic coronavirus spillover: doi.org/10.1172/JCI2...
Charlie Fricke & Stanley Perlman comment on Nicholas You Zhi Cheang et al.: doi.org/10.1172/JCI1...
6-Hydroxydopamine promotes antitumor immunity through macrophage remodeling beyond sympathetic ablation: Neuron www.cell.com/neuron/fullt...
Group 2 innate lymphoid cells rely on specific receptors at different stages to exit the gut and travel to the lungs and other organs during helminth infections.
Learn more in #ScienceImmunology: https://scim.ag/4b7lDtc
A new study published in Nature Medicine shows that CD19×CD3 and BCMA×CD3 T cell engagers improve disease outcomes in patients with treatment-refractory #AntisynthetaseSyndrome and #SystemicSclerosis.
👉 Read the paper: https://go.nature.com/4cxHN92
👉 Listen to the discussion: https://bit.ly/3OVwMo6
📢 New in @nature.com!
Work led by Dr. R. Brad Jones at Weill Cornell Medical College shows that persistent #HIV reservoir T cell clones resist immune clearance but remain vulnerable to sustained cytotoxic #TCell pressure.
🗒️ https://go.nature.com/4svfY62
🔊 https://bit.ly/3OVwMo6
Researchers led by Dr. Tak Mak at Princess Margaret Cancer Centre have shown that acetylcholine signaling in germinal center B cells helps regulate their selection and differentiation to shape high-affinity antibody responses.
1️⃣ Read: https://go.nature.com/4ud6NZl
2️⃣ Listen: https://bit.ly/3OVwMo6
The Lab Coats & Life Podcast is back, this time with video episodes! 🎉
Our very own Jason Goldsmith co-hosts the first episode! He discusses what trainees can do to better prepare for careers in today’s bioeconomy with President & CEO of BioTalent Canada, Rob Henderson.
New work led by Dr. Kerstin Ludwig at the University of Bonn employs genome sequencing to identify genetic and lifestyle factors linked to control of persistent #EpsteinBarrVirus infection and its association with autoimmune diseases. 🧬
📄: https://go.nature.com/4bfkSx3
🎧: https://bit.ly/3OVwMo6
AAI's IMMUNOLOGY2026™ program is shaping up to be an exciting and dynamic one. From cutting‑edge scientific sessions to can’t-miss lectures and networking events, this year’s annual meeting offers something for every immunologist.
📢 Explore the program and register today: https://bit.ly/46g64fU
