As war escalates, Iran’s universities face increasing fire Attacks have destroyed or damaged a wide range of academic and commercial research centers

As U.S. and Israeli strikes on Iran enter their sixth week, the nation’s academic institutions are increasingly under fire. https://scim.ag/4ceEkdK

SSP Epic Awards graphic with the text "Excellence in Publishing, Information Technology, & Communications." Includes the Science Magazine logo and mentions Science's TikTok. Text reads "2026 Finalist Social Presence."

The #EPICAwards from @scholarlypub.bsky.social "celebrate the outstanding achievements of individuals and teams who are advancing scholarly publishing through creativity, collaboration, and innovative solutions."

This year, Science’s TikTok is a finalist for Social Presence: https://scim.ag/4e7L8fE

The image is a Voronoi tessellation diagram depicting a cell in which clustering of FZD4 was induced by a synthetic antibody.

Don’t miss the new issue of #ScienceSignaling!

New insights into Wnt signaling could inform the design of rational ligands for therapy, a Review discusses the latest discoveries about the origins of brain metastases and potential targets, and more. https://scim.ag/4sfhSXL

"The greater risk is not that AI will eliminate jobs, but that its benefits will … accrue unevenly." Marie Lynn Miranda, University of Illinois Chicago

"… higher education must develop students into fluent, intelligent, and ethical users of #AI and work to ensure that the benefits of AI reach broadly across communities," writes Marie Lynn Miranda in a new #ScienceEditorial. https://scim.ag/4dvOxot

As Japan warms, cherry blossom displays are fading Some trees in southern Japan are already failing to reach peak bloom—a trend researchers predict will move north in the coming decades

Japan's beautiful cherry blossom displays are fading as climate change takes hold. Trees in southern Japan are already failing to reach peak bloom, and experts predict Kyoto, Osaka and Tokyo will soon face the same problem. @science.org www.science.org/content/arti...

Harnessing viral strategies to reverse cognitive dysfunction through the integrated stress response The integrated stress response (ISR) is essential for cellular homeostasis and cognitive function. We investigated how persistent ISR activation affects cognitive performance by studying the PPP1R15BR...

Out now in @science.org
Harnessing viral strategies to reverse cognitive dysfunction through the integrated stress response | Science www.science.org/doi/10.1126/...

My choice in @science.org whilst I was on vacation a week or so ago
DOI: 10.1016/j.cell.2025.12.007
Multimodal supramolecular targeting chimeras enable spatiotemporally resolved protein degradation in vivo

So excited to share our new @science.org podcast limited series The Normals! Out now!!

Listen here: www.science.org/content/podc...

Courtney Schreiber

🎉 Congratulations to Courtney Schreiber, winner of the 2026 BII & #ScienceTranslationalMedicine Prize for Innovations in #WomensHealth for her innovative work in redefining clinical care and testing for women experiencing early pregnancy loss.

Learn more on #WorldHealthDay: https://scim.ag/48tyrYT

Pearling drives mitochondrial DNA nucleoid distribution The distribution of mitochondrial DNA–containing nucleoids is essential for mitochondrial function and genome inheritance; however, no known mechanisms can explain nucleoid segregation or their regula...

Out now in @science.org
Pearling drives mitochondrial DNA nucleoid distribution | Science www.science.org/doi/10.1126/...

Pathways to pain: graphic illustrating the symptoms and mechanisms of endometriosis. Panel 1: diagram of the pelvic area showing common locations of lesions and cysts: the abdominal wall, the peritoneal membrane, the ovaries, between the uterus and rectum, and the vagina. Panel 2: Illustration of a reproductive system with endometriosis, showing locations of lesions and an ovarian cyst, as well as menstrual blood flowing out of the fallopian tube, which is thought to seed lesions. Panel 3: comparison of neutrophils in the menstrual effluent (ME) of women with endometriosis versus without; with endometriosis, the neutrophils have shrunken, many-lobed nuclei and vacuoles in their cytoplasm. Panel 4: Illustration of immune factors involved in endometriosis lesions: decreased natural killer cells, and increased neutrophils and macrophages.

A scientist is helping uncover the role of the immune system in endometriosis—while managing the disease herself.

Learn more on #WorldHealthDay: https://scim.ag/4oDvjAa

Copper supports regulatory T cell energetic state to sustain peripheral immune tolerance Slc31a1-mediated copper uptake maintains regulatory T cell function and peripheral immune tolerance.

A new #ScienceImmunology study finds that patients with rheumatoid arthritis have increased copper levels in regulatory T cells, which could guide new therapeutic strategies for autoimmune conditions. https://scim.ag/3O6hPzo

Strategies for achieving healthy, sustainable, and equitable dietary transitions The industrialization of global food systems has led to dietary changes that harm both health and the environment. If global food systems are to meet the needs of a growing population for healthy, env...

In a new #ScienceReview, researchers examine the evidence for how global diets have changed and strategies that could transition food systems toward a healthier future.

Learn more on #WorldHealthDay: https://scim.ag/4siRJaH

World’s most dangerous bird has bizarre, glowing headgear Structures on cassowaries’ skulls fluoresce under UV light, hinting at a hidden visual signal

Often labeled “the world’s most dangerous birds,” cassowaries just got even more intriguing. https://scim.ag/4bNnfIT

This month’s cover features a close-up image of a weathered bronze statue covered in copper patina.

The April 2026 issue of #ScienceImmunology is out!

This month's cover highlights how copper can "lend regulatory T cells a hand" by sustaining their metabolic fitness and peripheral immune tolerance. Learn more about this research and more: https://scim.ag/4sma5aU

Relics of an ancient sandstorm on Mars point to Earth-like winds Curiosity rover finds what may be the first direct evidence that Mars once had a thick atmosphere

The martian atmosphere is currently 200 times thinner than that of Earth. A 3 billion-year-old sandstorm recorded in the rocks could be the first direct evidence that wasn't always so. My latest for @science.org.🧪⚒️ 🚀🪐

The map highlights Wadi Moghra, Egypt (star), which is the discovery site of Masripithecus—the first definitive North African ape—alongside key Miocene hominoid localities (see table S1) across Afro-Arabia and Eurasia. Arrows indicate inferred dispersal routes based on the phylogenetic and biogeographic analyses presented here. The inset phylogeny places Masripithecus as the closest sampled sister taxon of crown Hominoidea. At lower left, a life reconstruction of Masripithecus based on the Masripithecus mandible combined with the facial morphology of the middle Miocene hominoid Pierolapithecus. [Illustration: M. Antón]

A newly discovered fossil ape suggests the closest ancestors to modern apes may have emerged in northern Africa, outside the traditionally studied regions of East Africa.

Learn more in Science: https://scim.ag/4uSvmLJ

Complete biosynthesis of psychedelic tryptamines from three kingdoms in plants Tryptamine psychedelics from plants, fungi, and toads are produced in planta through cross-kingdom pathway reconstruction.

Researchers in #ScienceAdvances have reconstructed the full biosynthetic pathways of five natural psychedelics in one plant system. https://scim.ag/3PLLIFP

Buried in a museum drawer for nearly 50 years, a fist-size fossil has handed paleontologists the evidence they’d been hunting for: unmistakable claws on one of the oldest known relatives of spiders and scorpions.

Learn more: https://scim.ag/4sdKT6m

Divergent and programmable skeletal remodeling of complex macrocycles with a small method set The bioactivity of complex organic macrocycles can vary unpredictably with their three-dimensional structural contours. Here, we present a streamlined, programmable and systematic strategy for skeleta...

In @science.org for chemsky, Amir Hoveyda's group report a remarkably streamlined approach to precise expansion or contraction of macrocycles

www.science.org/doi/10.1126/...

A recent #ScienceRobotics study demonstrates that haptic feedback from wearable upper body exoskeletons can improve coordination between violin duos more effectively than visual cues.

Learn more: https://scim.ag/4bFHZC8

A man towers over a building that says university on one side and town hall on the other, with text: I worried my science wasn’t making an impact. So I ran for elected office

"… as a researcher who’s had his share of scientific disagreements with other researchers, I have been able to work with others whose viewpoints differ from mine—an approach that is needed in these times of intense political polarization." #ScienceWorkingLife https://scim.ag/41JHwsP

SWOT detects dispersive tsunami tied to a near-trench source in the 2025 Kamchatka earthquake Tsunamis from large subduction earthquakes pose severe coastal hazards, yet their genesis near the trench remains poorly constrained by land-based seismic geodetic data and distant deep-water sensors....

Thanks to a satellite that happened to be flying over the 2025 Kamchatka tsunami not long after it formed, researchers in Science have unprecedented insights—even more than land-based tools could provide—into the development and spread of this catastrophic wave. https://scim.ag/41AaATt

An Alzheimer’s blood test is getting popular. But who really needs it? Overuse of the p-tau217 biomarker could push healthy people toward unnecessary drugs, scientists fear

Overuse of the p-tau217 biomarker could push healthy people toward unnecessary drugs, scientists fear. https://scim.ag/4sZprTu

Talk about an in-flight meal.

Last year, researchers reported on capturing rats hunting bats by grabbing them from the sky.

Learn more on #WorldRatDay: https://scim.ag/47vw4Ve

This photograph shows a female standard fancy rat—a domesticated variant for the pet trade.

A 2024 special issue of Science explored the complex and close associations rats share with humans—from their ubiquity in the human environment to their crucial role as biomedical models.

🐀 Learn more on #WorldRatDay: https://scim.ag/46VBOrb

Slasher sequel: Trump again proposes major cuts to U.S. science spending Science advocates urge Congress to reject 2027 budget plan

If at first you don’t succeed, try, try again.

That appears to be the thinking behind the 2027 budget request to Congress that President Donald Trump unveiled today. https://scim.ag/4sRnw3x

Illustrated graphic showing the Artemis II mission path, which will loop around the moon and then return to Earth. This path takes the Orion capsule outside Earth's magnetosphere, where it will be subject to solar particle events (shown as orange arrows, coming from the direction of the Sun) and galactic cosmic rays (shown as red arrows, coming from multiple directions). Most astronauts fly in low-Earth orbit, where Earth's magnetic field blunts much of the radiation, leaving microgravity as the main health stressor.

The Artemis II mission will provide a key test of how the human body responds to deep space radiation—the top health concern for humans living beyond Earth for extended periods.

Learn more: https://scim.ag/46p5BrA

Live human pancreas slice with islet cells stained red.

With the potential to limit T cell activity locally, a new drug called ImmTAAI may enable targeted immunoregulation treatment for type 1 diabetes.

Learn more in this week’s issue of #ScienceAdvances: https://scim.ag/3NQusPc

Self-regulating hydrogel for diabetic wound healing: From animal models to a pilot clinical study Self-regulating hydrogel controls therapeutic ion release for accelerated diabetic wound healing in clinic trials.

Researchers in #ScienceAdvances have developed a self-regulating hydrogel that enhances diabetic wound healing.

Learn more: https://scim.ag/4m9XyFU