#DALISPIM

The future of human clinical sample research is 3D.

This #FluorescenceFriday data (🔈 sound on!) from Clarence Yapp + Seo Woo Choi shows multiplexed labeling in human tonsil and colon samples imaged on #DALISPIM at 9X.

Register for our 4/30 webinar to learn more: bit.ly/4v9aXC1

Heading to Stockholm this weekend for #FOM2026? You can learn about #DALISPIM and our other 3D microscopy innovations in Dr. Andrew Allan’s talk, “From Tissue to Terabytes: An End-to-End Integrated Solution for Whole-Organ Light-Sheet Imaging”!
🗓️ Tuesday, 3/31 at 16:50 - 17:10
📌 Room M12

Join us for a webinar on the future of human clinical sample research with @harvardlab.bsky.social! Learn how advances in 3D #microscopy are enabling more accurate cell classification & exploration of novel biology, focusing on samples from melanoma patients. Register: bit.ly/4s4va9G #DALISPIM

Three scientists in semi-fpormal wear stand in a lab space. One of them cuts a ribbon with big scissors in front of a new microscope that says "DALISPIM" on it. There is a large "GRAND OPENING" banner hanging in the front of the picture, and colorful balloons everywhere.

Four scientists stand in casual wear in a lab space, smiling, around a microscope with "DALISPIM" written on the front. One of them stands behind the microscope comically pointing at it dramatically.

Happy #MicroscopyMonday! Our Head of Innovation Hsuan Lee shared these photos from Peter Sorger's lab (@harvardlab.bsky.social), where we just installed our first #DALISPIM open-top light sheet microscope. Stay tuned for another exciting announcement later this week!

How long does it take to get #FluorescenceFriday data from an organoid on your microscope? With #DALISPIM, it only took us 53 seconds per channel (MAP2 in cyan, and Pax6 in yellow) – and it can be even faster! Learn more: bit.ly/49pqjKd

The ideal #MicroscopyMonday combination: high-res data, low-effort protocol. Get a close-up look of cortical neurons in this segment of mouse brain hemisphere, imaged with #DALISPIM at 9X magnification in a 12-well plate.

Change how you see 👀 your samples with #DALISPIM light-sheet imaging. Here, nuclear staining (magenta) shows thick layers of retinal cells on the back of the eyeball connecting to the optic nerve, with a thin layer of cells over the cornea. What else do you want to see labeled? #FluorescenceFriday

Neutrophil Extracellular Traps (NETs) are fibrous structures released by immune cells to bind and kill pathogens. In collaboration with Dr. Mark Looney's lab at @ucsfhealth.bsky.social, we used #DALISPIM to visualize 3D NET formation (magenta) triggered by inflammation in a mouse lung. 🫁

At first, these may look like individually mounted samples. But all 12 datasets were captured at once, directly in a 12-well plate, using our new open-top #DALISPIM light sheet microscope.🔬

Vasculature (CD31) in magenta, parvalbumin cells (endogenous tdTomato) in yellow, and nuclei (DAPI) in cyan.