On the left, a photo of a rat being used in the forced swim test (credit to PETA). On the right, the following text: “New systematic review. Forced swim test papers have “inflated” results. Mirrors previous findings that published animal behavioral experiments are of low quality. ““Incomplete reports have precluded the assessment of internal and external validity of primary studies and accurate estimate of CES [combined effect size] for the FST.”” At the bottom, this citation: “Tamires et al. DOI: 10.1097/FBP.0000000000000844.”
New #SystematicReview finds a "remarkable" level of publication bias in experiments using the #ForcedSwimTest for antidepressant screening.
Combined with incomplete reporting, this compromised effect size estimates and raises "concerns about the validity of the FST literature."
🧵
🧪 #sysrev