#Hbond

Unveiling Repulsion in Intramolecular H-Bonded Systems Intramolecular H-bonds govern molecular conformation and play critical roles in pharmaceutical design, catalysis, and supramolecular chemistry. Despite this, the experimental influence of ortho-substi...

Worth reading if trying to exploit intramolecular hydrogen bonding in #ADME optimization: Smolyar & Cockroft (2025) Unveiling Repulsion in Intramolecular H-Bonded Systems. JACS 47:12381-12385 #Hbond #PhysChem #DrugDesign #MedChem #cheminformatics #OpenAccess #chemsky 🧪
doi.org/10.1021/jacs...

Ph3AsO as a Strong Hydrogen-Bond Acceptor in Cocrystals with Hydrogen Peroxide and gem-Dihydroperoxides | Inorganic Chemistry pubs.acs.org/doi/10.1021/... Virant and co-workers @InorgChem #arsenic #Ph3AsO #Hbond #acceptor #H2O2 #dihydroperoxides #cocrystals

Guest-Molecule-Induced Glass-Crystal Transition in Organic–Inorganic Hybrid Antimony Halides | Inorganic Chemistry pubs.acs.org/doi/10.1021/... Qi, Cao, Du, and co-workers @InorgChem #antimony #halides #water #Hbond #OIHMH