Wee1-AS, a #lncRNA, protects against #MASLD by repressing #Wee1 and stabilizing #CYCLINB1 to activate CDK1-driven mitochondrial #FattyAcidOxidation, while WEE1 inhibition or the human homolog LNC106435.1 similarly improves mitochondrial function.
#STTT: doi.org/10.1038/s413...