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Latest posts tagged with #eNeuro on Bluesky

Posts tagged #eNeuro

How blind people map their surroundings using sound Researchers linked neural activity to how blind individuals determine the location of objects by integrating echoes from mouth clicks into a representation of their surroundings.

From our latest paper published in #eNeuro and the work done at @skeriresearch.bsky.social

How blind people map their surroundings using sound | EurekAlert! www.eurekalert.org/news-release...

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Did you know you could publish confirmation studies and negative results in #eNeuro? Learn more about the many paper types that can be submitted. vist.ly/4xnkq

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New in #eNeuro: García-Lázaro and Teng linked neural activity to how blind individuals determine the location of objects by integrating echoes from mouth clicks into a spatial representation of their surroundings.
https://doi.org/10.1523/ENEURO.0342-25.2026

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AAV-Based Bright and Sparse Labeling of Versatile Neurons Adaptable in Cre-Dependent Genetic Backgrounds Sparse labeling techniques are essential for morphological analysis of the central nervous system. Various sophisticated strategies have been developed, but conventional methods, such as Golgi–Cox staining and biocytin injection, remain widely used. Recent advances in adeno-associated virus (AAV) technology have enabled sparse neuronal labeling in rodents, either through postnatal AAV injection or by coinjecting a dilute Cre recombinase-expressing driver with a Cre-dependent amplifier. However, postnatal AAV injection requires prior preparation, and Cre-dependent systems are incompatible with Cre-expressing or floxed genetic backgrounds. Here, we present a Cre-orthogonal AAV–based sparse labeling method that utilizes Supernova technology in male and female mice. We employed Flpe recombinase to achieve Cre-independent labeling. A retro-orbital injection of PHP.eB AAVs failed to label neurons, whereas local injection enabled the bright and sparse labeling of multiple neuronal types, including cerebellar neurons. The labeled neurons were sufficiently bright to visualize fine structures, such as dendritic spines, without the need for immunostaining. This method is compatible with both Cre-expressing and floxed genetic backgrounds. Furthermore, we demonstrated that the labeled neurons can be manipulated by the coinjection of a Flpe-dependent third virus. This straightforward and flexible approach is applicable across various genetic backgrounds and can be readily integrated into existing experimental systems.

#eNeuro | AAV-Based Bright and Sparse Labeling of Versatile Neurons Adaptable in Cre-Dependent Genetic Backgrounds
https://doi.org/10.1523/ENEURO.0314-25.2026

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#eNeuro | Parvalbumin Neuron–Targeted Loss of Alzheimer’s Disease Risk Gene BIN1 Is Insufficient to Drive Cognitive or Network Excitability Changes
https://doi.org/10.1523/ENEURO.0304-25.2026

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#eNeuro: Quansah Amissah et al. developed an open-source restraint system that allows high-quality fMRI in fully awake rats, eliminating the need for anesthesia. https://doi.org/10.1523/ENEURO.0390-25.2026

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#eNeuro | Transcriptional Changes Fade Prior to Long-Term Memory for Sensitization of the Aplysia Siphon-Withdrawal Reflex
https://doi.org/10.1523/ENEURO.0477-25.2026

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#eNeuro | Replating Induces mTOR-Dependent Rescue of Protein Synthesis in Charcot–Marie–Tooth Diseased Neurons
https://doi.org/10.1523/ENEURO.0337-25.2026

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A new #eNeuro commentary proposes investing in high-quality science education yields benefits beyond literacy and economic growth, contributing to public health by shaping brain health across the lifespan.
https://doi.org/10.1523/ENEURO.0036-26.2026

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#eNeuro Blog | Reviewing Editor Adrien Peyrache highlights the work from Khouma et al., which explores a neuropeptide released by sleep-active neurons in the hypothalamus that promotes wakefulness by inhibiting histaminergic neurons.
https://blog.eneuro.org/2026/03/editors_pick_peyrache

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#eNeuro | Aperiodicity in Mouse CA1 and DG Power Spectra
https://doi.org/10.1523/ENEURO.0136-25.2026

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#eNeuro | Numbers of Granule Cells and GABAergic Boutons Are Correlated in Shrunken Sclerotic Hippocampi of Sea Lions with Temporal Lobe Epilepsy
https://doi.org/10.1523/ENEURO.0389-25.2026

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Very excited that this is now publicly available in #eNeuro! 🍸🧠🧬
And very grateful for my co-authors & their contributions.
#neuroepigenetics #transcriptomics

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New in #eNeuro from Periandri et al: Systematically comparing brain markers affected by brief versus long-term exposure to alcohol in mice unveils shared and different mechanisms that may inform alcohol use disorder treatment development. vist.ly/4wpe2

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Parvalbumin Neuron–Targeted Loss of Alzheimer’s Disease Risk Gene BIN1 Is Insufficient to Drive Cognitive or Network Excitability Changes Bridging integrator 1 ( BIN1 ) is one of the strongest genetic risk factors for Alzheimer’s disease (AD), yet its function in the brain and role in AD remain unclear. Neuronal BIN1 isoform levels are ...

PV or not PV? That was the question.

BIN1 is a leading AD risk factor and critical in inhibitory neurons. However, BIN1 loss from PV INs is not enough to disrupt the system.

Check out some of my graduate work recently published in #eNeuro @sfnjournals.bsky.social
www.eneuro.org/content/13/3...

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#eNeuro | Automatic, But Not Autonomous: Implicit Adaptation Is Modulated by Goal-Directed Attentional Demands
https://doi.org/10.1523/ENEURO.0243-25.2026

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Time to Clean Out the File Drawer!
Did you know that #eNeuro accepts confirmation studies and negative results? Learn more about different paper types that can be submitted: vist.ly/4wiee

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#eNeuro Opinion | Challenging popular assumptions, Fricke and colleagues argue that certain forms of Social Media content may enhance motor skill acquisition and function.
https://doi.org/10.1523/ENEURO.0382-25.2026

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#eNeuro | Robust Representation and Nonlinear Spectral Integration of Harmonic Stacks in Layer 4 of the Mouse Primary Auditory Cortex https://doi.org/10.1523/ENEURO.0038-26.2026

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#eNeuro | Transcranial Static Magnetic Stimulation Dissociates the Causal Roles of the Parietal Cortex in Spatial and Temporal Processing
https://doi.org/10.1523/ENEURO.0366-25.2026

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#eNeuro: Computational neuroscientists often attempt to understand the brain using analyses that assume stronger neural signals are more important to the system. This work challenges that core assumption.
https://doi.org/10.1523/ENEURO.0461-25.2026

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#eNeuro blog Reviewer Spotlight | Find strategies for reviewing from Jai Yu and learn about his work studying how distributed brain networks support cognition.
https://blog.eneuro.org/2026/03/reviewer_yu

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#eNeuro | Building an Ecosystem of Seizure Localization Methods: Neural Fragility as the First Step
https://doi.org/10.1523/ENEURO.0340-25.2026

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#eNeuro | Short-Term Perceptual Training Modulates Neural Responses to Deepfake Speech But Does Not Improve Behavioral Discrimination
https://doi.org/10.1523/ENEURO.0300-25.2026

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#eNeuro Commentary | Learning Environments and Brain Health: A Neuroeducational Perspective https://www.eneuro.org/content/13/3/ENEURO.0036-26.2026

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New in #eNeuro from Boebinger et al: Compared to young adults, older people with and without Parkinson's disease have larger brain responses and muscle signals that hinder their balance recovery ability. vist.ly/4vv4v

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#eNeuro | Open-Source Platform for Adjustable Training Regimes in Freely Moving and Head-Fixed Mice
https://doi.org/10.1523/ENEURO.0459-25.2026

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#eNeuro Theory/New Concepts | Representation Biases: Variance Is Not Always a Good Proxy for Importance
https://doi.org/10.1523/ENEURO.0461-25.2026

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#eNeuro | Changes in Palatability Processing across the Estrous Cycle Are Modulated by Hypothalamic Estradiol Signaling
https://doi.org/10.1523/ENEURO.0225-25.2026

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#SnapshotsinNeuroscience | Featured on the #eNeuro blog from Soma et al. vivid vertical tracks targeting the Cornu Ammonis 1 region of the dorsal hippocampus of a transgenic rat. Photo Credit: Shogo Soma
blog.eneuro.org/2026/03/snapshots_rat_do...

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