Cartoon drawing. First panel has as title: Hard sweep: diversity much reduced. Second panel has as title: Soft sweep: diversity not much reduced. In the first panel a bold person with glasses, in their body there are circles representing viral particles, they take medication, most viral particles disappear, but one is able to resist and now the entire population looks like that one particle. The soft sweep panel has someone with curly hair. They also take drugs, two viral particles survive and now the viral population consists of two types.
Made a drawing to explain what a soft sweep is (and a hard sweep) in the context of drug resistance evolution in a viral population within a person's body.
Anyone teaching about selective sweeps? Feel free to use.
#populationgenetics #HIV #drugresistance #evolution #PopulationGenomics