Latest posts tagged with #Autophagy on Bluesky
⭐️April is #GraduateStudentAppreciation Month!👩🏻🎓
Join the #FriedmanBrainInstitute in celebrating Yue Lab's Ayris Izmirli. Her research topics are #HuntingtonsDisease & #Autophagy. A student leader, Ayris holds several prominent roles across mentorship & community health. 🎉SHOUT OUT to Ayris Izmirli👏
#LKB1 loss in alveolar epithelial cells reduces #autophagy, induces #EMT, and drives #PulmonaryFibrosis via epithelial–fibroblast crosstalk, highlighting CAB39L‑LKB1 signaling as a potential therapeutic target in IPF. @unisouthampton.bsky.social
#OpenAccess: doi.org/10.1016/j.ge...
Diagram showing the proposed mechanism by which EGCG inhibits HBV production through activating the AMPK/TFEB pathway to promote autophagic degradation of viral components.
🫖 Green tea vs. Hepatitis B?🧪
EGCG may:
• Activate AMPK/TFEB 🧬
• Boost autophagy
• Reduce HBV load
Blocking autophagy reverses its effect—key mechanism.
🔗 doi.org/10.1016/S187...
#HepatitisB #EGCG #Autophagy #CJNM
cGMP–PKG signaling attenuates #AorticValveCalcification by activating ULK1-mediated #Autophagy and inhibiting #Osteogenic differentiation, suggesting a promising #TherapeuticTarget against calcific #AorticValveDisease.
#STTT #OpenAccess: doi.org/10.1038/s413...
☕Chica et al. combined genetic network mapping, time-resolved imaging and deep learning to generate a dataset called AutoDRY that describes multilayered control of #autophagy and uncovers new regulatory pathways.
bit.ly/4sfZa2g
Investigating the Potential of Electrolyzed Hydrogen Water in Enhancing Chemosensitivity to Cancer Drugs #Japan #Tokyo #Autophagy #Molecular_Hydrogen #Electrolyzed_Hydrogen_Water
#Autophagy and #mTOR papers from last week, enjoy with a chocolate egg or two 🐣
biomed.news/bims-auttor/...
As a medical school professor, I teach that autophagy -- the body's cellular recycling system -- is one of the most powerful defenses against a... https://fastforhealth.co/ https://pubmed.ncbi.nlm.nih.gov/41372565/
#Autophagy #FastingMimickingDiet #MetabolicHealth #Longevity #HealthLongevitySecrets
A novel #compound enhances #CellularWaste clearance in #BrainCells, reduces harmful proteins, and prevents #NeuronDeath in #FrontotemporalDementia models, suggesting a potential treatment for #NeurodegenerativeDiseases.
#Aging #Dementia #CognitiveDecline #Autophagy
Resistance to prolonged darkness in plants steered by N-terminal acetylation | New study by Gong et al. Markus Wirtz lab @giglionelab.bsky.social Tanja Bange lab #NatB #autophagy #N-degron #proteostasis www.nature.com/articles/s41...
This week #JournalClub @labsoap.bsky.social
#Src #lysosome #autophagy #exocytosis welcome to the upside-down 😱 @science.org www.science.org/doi/10.1126/...
#Autophagy and #mTOR papers from last week, enjoy thanks to @biomednews.bsky.social pre-selection!
biomed.news/bims-auttor/...
☕Xu, Li, Deng et al identify a ubiquitin-dependent degradation mechanism for cleaved GSDME mediated by TOLLIP through endocytosis and #autophagy. They show this modulates #pyroptosis, antitumor immunity and #chemotherapy response in mouse models.
👉https://rdcu.be/faqWC
bit.ly/4c9WBtJ
Dean David Perlmutter, MD opened our Pediatric Research Retreat with a powerful keynote on Alpha-1 Antitrypsin Disease 🔬 Genetic modifiers + autophagy-targeting drugs = incredible promise for liver disease! #Alpha1 #Autophagy #PedsResearch #LiverDisease @washumedicine.bsky.social
Only few days left ! Send us your #autophagy art before March 31st : cfatg.org/en/bourses/i...
29 hours left of my 72 hour fast. Yesterday midday until midnight was hell. Let's hope this mystical autophagy kicks in.
#autophagy #fast
New research in #GENETICS highlights #autophagy as a key mechanism underlying ASC1-mediated modulation of TDP-43 toxicity in #yeast, suggesting autophagy as a promising therapeutic target in neurodegenerative diseases, such as #ALS. buff.ly/3xi2PAr
🧬 New from Lambton et al!
📄 Bi-allelic ATG12 variants impair #autophagy and cause a neurodevelopmental disorder
Helene Knævelsrud
Our Cell Scientist to Watch is Helene Knævelsrud @helene-knavelsrud.bsky.social. We spoke to Helene about her career, her research and her advice on mentorship.
journals.biologists.com/jcs/article/...
#autophagy #kidneycancer #mentorship #conferences #procrastination #advocacy #beer
📣The 13th CFATG Scientific Days on Autophagy, will be held next October at FIAP Jean Monnet in #Paris.
👉 Registrations are open!
🔗 www.atoutcom.com/autophagy/
#CFATG2026 #autophagy
@cfatg.bsky.social @sbcf.bsky.social @univparissaclay.bsky.social @gdr-imabio-ysn.bsky.social
The feeling of getting super excited because you’re about to finish — and soon preprint — a paper you’ve been working with @shanshuo.bsky.social on for 5 years… indescribable 🥳. #preprint 🌱 #PlantScience #autophagy ♻️ #immunity #proteostasis #ERCStG #theustunlab
This #STTT study shows that activation of the cGMP–PKG signaling pathway attenuates #AorticValveCalcification by promoting ULK1-mediated #Autophagy, which suppresses #Osteogenic differentiation in valvular interstitial cells.
#OpenAccess: doi.org/10.1038/s413...
#Autophagy and #mTOR papers from last week, very interesting stuff going on in the field, don’t miss it! 👇🏼
biomed.news/bims-auttor/...
👋Our March issue is out!
Cover: #Adipose – #tumor in #immune escape
👉Reviews on: #metabolism #hematopoiesis ; #amnion ; #brain #lipids
🔬 #mitochondria #LipidDroplets #aging #autophagy #mechanobiology #neurodegeneration #ferroptosis #chromatin #metastasis & more!
www.nature.com/ncb/volumes/...
Articles in our latest collection focus on the roles of ATG9 and LC3 interacting regions, plus mechanisms of selective #autophagy involving Rab #GTPases, #mitophagy, and #pexophagy. 👉 rupress.org/jcb/collecti...
#GRC
ATG9A facilitates closure of mammalian autophagosomes. From Ruheena Javed, Vojo Deretic and colleagues: rupress.org/jcb/article/...
📕 Part of #Autophagy 2026 👉 rupress.org/jcb/collecti...
#GRC
The #mitophagy receptors BNIP3 and NIX mediate tight attachment and expansion of the isolation membrane to #mitochondria. From Shun-ichi Yamashita, Ritsuko Arai, Tomotake Kanki, Satoshi Waguri et al. rupress.org/jcb/article/...
📕 Part of #Autophagy 2026 👉 rupress.org/jcb/collecti...
#GRC
Trachsel-Moncho, @annesimonsen.bsky.social et al. identify the endosomal protein SNX10 as a modulator of piecemeal #mitophagy of OXPHOS machinery components and mitochondrial homeostasis. rupress.org/jcb/article/...
📕 Part of #Autophagy 2026 👉 rupress.org/jcb/collecti...
#GRC
Distinct TRAPP complexes activate Ypt/Rab #GTPases in #secretion and #autophagy. New study from Valeriya Gyurkovska, Nava Segev and colleagues (University of Illinois at Chicago): rupress.org/jcb/article/...
#Biochemistry #Membrane #lipid
