#CausalVariants

Single-cell multiome and enhancer connectome of human retinal pigment epithelium and choroid nominate causal variants in macular degeneration - PubMed Age-related macular degeneration (AMD) is a leading cause of vision loss worldwide. Genome-wide association studies (GWASs) of AMD have identified dozens of risk loci that may house disease targets.…

New Cell Reports study moves GWAS from association to causation, using single-cell multiomics to pinpoint causal variants driving macular degeneration.
#Genomics #GWAS #CausalVariants #PrecisionMed #AMD #complement buff.ly/w7b7CPU