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#MassCytometry

Latest posts tagged with #MassCytometry on Bluesky

Posts tagged #MassCytometry

A group picture of staff and users of the Mass Cytometry facility

A group picture of staff and users of the Mass Cytometry facility

#MethodMonday 🧪

Behind every powerful technique is a team of dedicated scientists.

Meet the MRC WIMM Mass Cytometry Facility, where our mass cytometer helps researchers explore biology at single-cell resolution.

#WIMMResearch #MassCytometry #CoreFacilities #ScienceBehindTheScenes #MeetTheTeam

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#MethodMonday 🧪

What makes #MassCytometry such a powerful tool for the #MRCWIMM researchers?

#WIMMResearch #Immunology #Hematology #SingleCellScience

@medsci.ox.ac.uk @drakesmith-lab.bsky.social 🧬

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Mass Cytometry
Mass Cytometry YouTube video by MRC Weatherall Institute of Molecular Medicine

Each metal tag = one unique signal , all at single cell resolution → giving researchers incredibly detailed cellular maps.

Curious to dive deeper? 🎥 Watch the video: youtu.be/njlYmWdsElM

#MassCytometry #CyTOF #WIMMResearch #Immunology #SingleCellAnalysis 🧪🧬

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#MethodMonday 🧪

So… how does #MassCytometry actually work? 🤔

1. Cells are stained with antibodies tagged to rare heavy metals
2. Each cell is vaporised and ionised in a plasma
3. Ions are separated by their mass and detected in a time-of-flight (TOF) mass spectrometer

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Using #MassCytometry, this #STTT study characterized the #ImmuneLandscape of #ESCC, demonstrating that targeting CD39⁺ T cells & PD-L1⁺ macrophages can reprogram the #TumorMicroenvironment to optimize #Immunotherapy response.

#OpenAccess: doi.org/10.1038/s413...

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#MethodMonday From now on, each week, we’ll highlight a different research method used at the #MRCWIMM, breaking down how it works and why it’s important. 🧪

Here we go!

Ever wondered how scientists can measure dozens of proteins on a single cell? #MassCytometry makes this possible!

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Mass spectrometric imaging and quantitative analysis of the in vivo biodistribution of trastuzumab using a rhodium(III) sarcophagine complex Mass cytometry with antibodies labelled with stable metal isotopes enables both sensitive imaging and the quantification of protein expression in biological samples. Typically, these specimens are exp...

🔓 #OpenAccess

𝐌𝐚𝐬𝐬 𝐬𝐩𝐞𝐜𝐭𝐫𝐨𝐦𝐞𝐭𝐫𝐢𝐜 𝐢𝐦𝐚𝐠𝐢𝐧𝐠 𝐚𝐧𝐝 𝐪𝐮𝐚𝐧𝐭𝐢𝐭𝐚𝐭𝐢𝐯𝐞 𝐚𝐧𝐚𝐥𝐲𝐬𝐢𝐬 𝐨𝐟 𝐭𝐡𝐞 𝐢𝐧 𝐯𝐢𝐯𝐨 𝐛𝐢𝐨𝐝𝐢𝐬𝐭𝐫𝐢𝐛𝐮𝐭𝐢𝐨𝐧 𝐨𝐟 𝐭𝐫𝐚𝐬𝐭𝐮𝐳𝐮𝐦𝐚𝐛 𝐮𝐬𝐢𝐧𝐠 𝐚 𝐫𝐡𝐨𝐝𝐢𝐮𝐦(𝐢𝐢𝐢) 𝐬𝐚𝐫𝐜𝐨𝐩𝐡𝐚𝐠𝐢𝐧𝐞 𝐜𝐨𝐦𝐩𝐥𝐞𝐱 by Michelle T. Ma 𝘦𝘵 𝘢𝘭.

#Masscytometry #rhodium #anti-tumor

🔗 doi.org/10.1039/D5QI00731C

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The two days of our meeting have flown by. We had the opportunity to listen to inspiring presentations, sharing experiences, gain valuable insights into the latest techniques and applications of #masscytometry, engage in insightful discussions, and establish new collaborations.

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After a successful day filled with exciting #masscytometry data and insightful discussions, we would like to thank all the speakers for their contributions.

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Many thanks to all our industry partners for supporting our meeting. During the Techno Bites, they impressed us with their latest innovations for #masscytometry.

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Diana Dudziak & Sabine Baumgart from Jena University Hospital and Axel Schulz, DRFZ, warmly welcomed the participants of the 8th German #MassCytometry User Forum in Jena. We are exited for inspiring presentations, engaging discussions and valuable exchanges throughout the event.

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