#phage

Protein and genomic language models uncover the unexplored diversity of bacterial immunity The bacterial pangenome contains a vast diversity of antiphage systems, whose overall extent is still unknown. In this study, we developed complementary machine learning approaches to systematically p...

5 days ago

#microsky #phagesky #phage defence

www.science.org/doi/10.1126/...

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Arbitrium phages can manipulate each other’s lysis/lysogeny decisions Many viruses can switch between lytic replication and dormancy (or lysogeny). It was recently discovered that some viruses that infect bacteria (known…

6 days ago

www.sciencedirect.com/science/arti...
#phage #phagesky

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PLOS Biology

@plosbiology.org

6 days ago

λcI857 lytic infections and host lysogenization following induction of lysogens embedded within Escherichia coli biofilms with either WT curli production (curli+) or no curli production (curli−). Host biofilms were inoculated with λcI857 lysogens and uninfected host cells at a 1:10 ratio and cultured for 72 h prior to λcI857 phage induction. The image shows a time series of biofilms inoculated with lysogens and uninfected E. coli hosts that either produce (top row) or do not produce (bottom row) curli extracellular matrix. The first image in each row was taken just after heat was applied to induce some biofilm-embedded lysogens to switch to the lytic infection cycle.

How do #bacteriophage life history strategies influence host invasion & inter- #phage competition in #biofilms? This study shows that spatial structure shapes invasion success, favoring temperate phages over lytic ones when diffusion is limited @plosbiology.org 🧪 plos.io/47Aripq

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PLOS Biology

@plosbiology.org

1 week ago

λcI857 lytic infections and host lysogenization following induction of lysogens embedded within Escherichia coli biofilms with either WT curli production (curli+) or no curli production (curli−). Host biofilms were inoculated with λcI857 lysogens and uninfected host cells at a 1:10 ratio and cultured for 72 h prior to λcI857 phage induction. The image shows a time series of biofilms inoculated with lysogens and uninfected E. coli hosts that either produce (top row) or do not produce (bottom row) curli extracellular matrix. The first image in each row was taken just after heat was applied to induce some biofilm-embedded lysogens to switch to the lytic infection cycle.

How do #bacteriophage life history strategies influence host invasion & inter- #phage competition in #biofilms? This study shows that spatial structure shapes invasion success, favoring temperate phages over lytic ones when diffusion is limited @plosbiology.org 🧪 plos.io/47Aripq

7 3 1 0

PLOS Biology

@plosbiology.org

1 week ago

λcI857 lytic infections and host lysogenization following induction of lysogens embedded within Escherichia coli biofilms with either WT curli production (curli+) or no curli production (curli−). Host biofilms were inoculated with λcI857 lysogens and uninfected host cells at a 1:10 ratio and cultured for 72 h prior to λcI857 phage induction. The image shows a time series of biofilms inoculated with lysogens and uninfected E. coli hosts that either produce (top row) or do not produce (bottom row) curli extracellular matrix. The first image in each row was taken just after heat was applied to induce some biofilm-embedded lysogens to switch to the lytic infection cycle.

How do #bacteriophage life history strategies influence host invasion & inter- #phage competition in #biofilms? This study shows that spatial structure shapes invasion success, favoring temperate phages over lytic ones when diffusion is limited @plosbiology.org 🧪 plos.io/47Aripq

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1 week ago

#microsky #phagesky

Temperate #phage better than lytic at infecting E. coli biofilms

journals.plos.org/plosbiology/...

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1 week ago

#phage #phagesky

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Rob Edwards

@linsalrob.bsky.social

1 week ago

So good to hang out with @lucyleef.bsky.social and @laurabonofiglio.bsky.social in Perth

Taking over the @abacbs.bsky.social Meetup to talk #phage

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@evgenii-protasov.bsky.social

1 week ago

#microsky #phagesky on #phage cocktails

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Evgenii Protasov

1 week ago

Parasitic connections: a patescibacterial epibiont, its methylotrophic gammaproteobacterial host, and their phages
#microbiology #bacteria #phage #virus #MicroSky
@asm.org
doi.org/10.1128/mbio...

5 2 1 0

Bacteriophage Lab of Institut Pasteur

@phagepasteur.bsky.social

1 week ago

Another week, another paper that we liked so much, we made a brief comment on

You should take a look! It's only a short thread 🧵

#Phage #Phagesky

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Bacteriophage Lab of Institut Pasteur

1 week ago

www.pnas.org/doi/10.1073/...

Phages drive the dissemination of antibiotic resistance genes by facilitating host adaptation to heavy metal stress

#phage #phagesky

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@phagepasteur.bsky.social

1 week ago

While more experimental evidence is warranted, this work motivated a vivid discussion in our team!
It also reminds us that we are still far from understanding #phage biology even after >100 years of research.

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Bacteriophage.news

@bacteriophagenews.bsky.social

2 weeks ago

We're partnering with Parallel Health, a company that is redefining what precision #phagetherapy looks like with their MD-03 Protocol™ - a comprehensive system that integrates #microbiome sequencing, personalized #phage serums, and clinical support. www.bacteriophage.news/parallel-hea...

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BE CLEAR with Bronchiectasis

@becleartoday.bsky.social

2 weeks ago

Living with #Mycobacterium abscessus (Mab)? You could help advance personalized
#phage therapy research, while potentially benefiting from future treatment options.
We're building a patient-focused Mab #biobank. Learn more: tolka.ai/biobank

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Cross-order detection of bacteriophage transduction in microbial communities using RNA barcoding - Nature Communications Bacteriophages are the most abundant life form on earth and can be applied to eliminate or engineer bacteria. Here, authors demonstrate RNA barcoding as a high throughput tool to measure bacteriophage...

2 weeks ago

#microsky #phagesky #phage

www.nature.com/articles/s41...

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The Phage

@thephage.bsky.social

2 weeks ago

Phage-Antibiotic Therapy Clears Spine Implant-Associated MRSA | The Phage A successful case report was published in the International Journal of Infectious Diseases, supporting personalized phage therapy treating chronic MRSA vertebral osteomyelitis

In a recently published peer-reviewed case report in the International Journal of #Infectious Diseases, a critical case of chronic MRSA Vertebral osteomyelitis involving spinal hardware was resolved using personalised #phage therapy.

#antibiotics #MRSA

www.thephage.xyz/news/phage-a...

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The Phage

@thephage.bsky.social

2 weeks ago

USDA-ARS Vaccine and Phage Research for Aquatic Health - The phage jobs USDA-ARS offers postdoctoral research opportunity in phage therapy, aquaculture disease prevention, vaccine development, and microbiology research.

The U.S. Department of Agriculture (USDA), through its Agricultural Research Service (ARS), is offering a Postdoctoral Research Opportunity at the Stuttgart National Aquatics Research Centre in Stuttgart, Arkansas, USA.

#phage #jobs #career

thephage.xyz/jobs/jobs/us...

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