Latest posts tagged with #HSCT on Bluesky
New in @jhumimmunity.org: Using single-cell RNA-seq, Manabu Wakamatsu, Hideki Muramatsu et al. @en.nagoya-u.ac.jp show that rhG-CSF suppresses IFNγ signaling and promotes B-cell differentiation in reticular dysgenesis, with potential benefits before #HSCT. rupress.org/jhi/article/...
Using single-cell RNA-seq, Manabu Wakamatsu, Hideki Muramatsu et al. @en.nagoya-u.ac.jp show that rhG-CSF suppresses IFNγ signaling and promotes B-cell differentiation in reticular dysgenesis, with potential benefits before #HSCT. rupress.org/jhi/article/...
#immunodeficiencies
#VIROMARKERS #HSCT study starts at Tor Vergata! 🧬
#IHI #HorizonEurope #HealthcareInnovation #MedicalResearch #ResearchAndInnovation #HIV #HDV #CMV @francinca.bsky.social @tyty4net.bsky.social @flaviamarzulli.bsky.social @eatgroup.bsky.social @ihieurope.bsky.social
Insightful session at EBMT 2026: Dr. Jon Salmanton-García @salmantongarcia.bsky.social presenting on rare fungal infections after HSCT (Fusarium, Scedosporium). Important perspectives on managing complex infections in immunocompromised patients. #EBMT2026 #HSCT #InfectiousDiseases
Hematopoietic stem cell transplantation as a curative treatment for Nck-associated protein 1-like (HEM1) deficiency: A first case report. From Julian Thalhammer, Wadih Abou Chahla @chulille.bsky.social and colleagues: rupress.org/jhi/article/...
#InbornErrorsOfImmunity #Therapeutics #HSCT
#VIROMARKERS study on #HSCT viral markers 🧬
#IHI #HorizonEurope #HealthcareInnovation #MedicalResearch #ResearchAndInnovation #HIV #HDV #CMV
@francinca.bsky.social @tyty4net.bsky.social @flaviamarzulli.bsky.social @eatgroup.bsky.social @ihieurope.bsky.social
@jhumimmunity.org: The first successful hematopoietic stem cell transplantation for HEM1 (NCKAP1L) Deficiency. A girl (5y) underwent #HSCT w/ a MSD after RTX, Alemtuzumab, TTF conditioning for recurrent infections and EBV-induced HLH and is fine 3y post HSCT. rupress.org/jhi/article/...
Thalhammer et al. report the first successful hematopoietic stem cell transplantation for HEM1 (NCKAP1L) Deficiency. A girl (5y) underwent #HSCT with a MSD after RTX, Alemtuzumab, TTF conditioning for recurrent infections and EBV-induced HLH and is fine 3y post HSCT. rupress.org/jhi/article/...
Unmanipulated bone marrow infusion without conditioning can rescue RECQL4-/- severe combined immunodeficiency. New study from Alexandra Grier and colleagues @chopresearch.bsky.social: rupress.org/jhi/article/...
#ClinicalPhenotypes #immunodeficiencies #InbornErrorsOfImmunity #SCID #HSCT
Hematopoietic stem cell transplantation following invasive mold infection in chronic granulomatous disease: insights from a case series and literature review. New study from Hugo Bes-Berlandier, Fanny Lanternier @hopitalnecker.bsky.social and colleagues: rupress.org/jhi/article/...
#CGD #HSCT
IPOPI was pleased to take part in the PID Symposium organised by the VIVA Foundation for Children with Cancer in Singapore.
Strengthening collaboration across disciplines remains essential to improve outcomes for people living with primary immunodeficiencies.
#PID #HSCT #RareDiseases #GlobalHealth
Bes-Berlandier, Lanternier et al @hopitalnecker.bsky.social describe the characteristics & clinical outcomes of chronic granulomatosis disease patients undergoing hematopoietic stem cell transplantation within 2 years after an invasive mold infection diagnosis rupress.org/jhi/article/...
#CGD #HSCT
🩸Brazilian pediatric consensus reviews 3 post-allogeneic #HSCT cell therapies: DLI to amplify GvL, stem cell boost for graft dysfunction, and MSC for refractory #GvHD. 🆓https://doi.org/10.46765/2675-374X.2025v6n1e309
#MedSky #hematology #oncology #oncopediatrics #JBMTCT
Hematopoietic stem cell transplant with a carrier donor rescues CD40L deficiency. New case report from Christen L. Ebens @umnpeds.bsky.social, Amir A. Sadighi Akha @mayoclinic.org and colleagues: rupress.org/jhi/article/...
#InbornErrorsOfImmunity #Therapeutics #HSCT
Lyytikäinen, Johansson et al. report two novel assays to characterize T cell function in two patients with DCLRE1C variants diagnosed with leaky severe combined immunodeficiencies (#SCID). rupress.org/jhi/article/...
#SCID #PrimaryImmunodeficiency #InbornErrorsOfImmunity #HSCT #ClinicalImmunology
@jhumimmunity.org: Ebens et al demonstrate successful allogeneic #HSCT of CD40L deficiency using an asymptomatic carrier mother donor w/ achievement of 32% CD40L expression, recovery of thymopoiesis, normal T cell diversity & functional outcomes of T & B cell interactions rupress.org/jhi/article/...
Ebens, Akha et al. demonstrate successful allogeneic #HSCT of CD40L deficiency using an asymptomatic carrier mother donor, with achievement of 32% CD40L expression, recovery of thymopoiesis, normal T cell diversity and functional outcomes of T and B cell interactions. rupress.org/jhi/article/...
Beyond survival: Multisystem long-term outcomes following #HSCT in chronic granulomatous disease. New study from Valentina Guarnieri, Reem Elfeky and colleagues @greatormondst.bsky.social: rupress.org/jhi/article/...
#InbornErrorsOfImmunity #immunodeficiencies #CGD
@esidsociety.bsky.social
In @jhumimmunity.org, Guarnieri, Elfeky et al. @greatormondst.bsky.social report long-term outcomes after #HSCT in children with chronic granulomatous disease. While survival is excellent, a wide range of autoimmune and organ-specific late effects emerge. rupress.org/jhi/article/...
#CGD
Guarnieri, Elfeky et al. @greatormondst.bsky.social report long-term outcomes after #HSCT in children with chronic granulomatous disease. While survival is excellent, a wide range of autoimmune and organ-specific late effects emerge. rupress.org/jhi/article/...
#CGD #InbornErrorsOfImmunity
Pediatric Acute Myeloid Leukemia: timing is critical.
The 2025 Brazilian consensus shows that any detectable MRD after HSCT predicts relapse and poor survival. Early, serial MRD monitoring is decisive, and delays can cost a cure.
doi.org/10.46765/267...
#HSCT #HemeOnc #HemeSky #MedSky #JBMTCT
HSCT yields satisfactory long-term outcomes in patients with PNP deficiency. OS was best in early-diagnosed patients without neurologic symptoms. Read in Blood: buff.ly/MhfvvBD #HSCT #BloodJournal
Fred Hutch is recruiting a full-time Associate Professor in the Translational Science & Therapeutics Division. We are seeking candidates with expertise in hematopathology and molecular pathology, and interest in #HSCT, #IMTX and lymphoid neoplasms. Apply: https://apply.interfolio.com/178338
Pleased to announce FDA approval of YARTEMLEA® (narsoplimab-wuug). First and only approved lectin pathway inhibitor therapy indicated for TA-TMA.
More info: bit.ly/497VHeF
#YARTEMLEA #narsoplimab #ComplementInhibition #RareDisease #TMAtreatment #NowApproved #MASP2inhibitor #tma #hsct #omeros #FDA
🩸This study shows that hematopoietic cell transplantation is curative for >150 inborn errors of immunity. In Wiskott–Aldrich syndrome, early transplant achieves ~91% 5-year survival, especially with robust donor myeloid chimerism.
doi.org/10.46765/267...
#HSCT #HemeOnc #HemeSky #MedSky #JBMTCT
Fred Hutch is recruiting a full-time Associate Professor in the Translational Science & Therapeutics Division. We are seeking candidates with expertise in hematopathology and molecular pathology, and interest in #HSCT, #IMTX and lymphoid neoplasms. Apply: https://apply.interfolio.com/178338
Fred Hutch is recruiting a full-time Associate Professor in the Translational Science & Therapeutics Division. We are seeking candidates with expertise in hematopathology and molecular pathology, and interest in #HSCT, #IMTX and lymphoid neoplasms. Apply: https://apply.interfolio.com/178338
💊FDA Approval | #Omisirge
First cellular therapy for severe aplastic anemia (#SAA) — Omisirge (omidubicel-onlv), the first #HSCT option for patients without a compatible donor. Restores blood & immune system.Faster recovery.Orphan Drug & Priority Review
🔗https://ow.ly/1PhU50XG3OJ
