This image is a flowchart and infographic detailing a study on polygenic risk scores for diabetes. It begins with genetic risk segmentation of 24,025 participants from the Malmö Diet and Cancer Study. The flow includes the segmentation into diabetes types: SAID, MARD, MOD, and SIDD, which are associated with coronary artery disease. It depicts genetic instruments and Mendelian randomization, leading to exposure and outcomes, including any ischemic stroke, large artery stroke, coronary artery disease, myocardial infarction, and coronary revascularization. The right side displays a bar graph showing odds ratios for these conditions.
The current study demonstrates that a high genetic susceptibility for moderate obesity-related diabetes can predict the onset of both diabetes and coronary artery disease. #DCare #Article
Read here ➡️ doi.org/10.2337/dc25-1711